1.4.2 Persistent aura without infarction

Description:
Aura symptoms persisting for one week or more without evidence of infarction on neuroimaging.

Diagnostic criteria:
A. Aura fulfilling criterion B
B. Occurring in a patient with 1.2 Migraine with aura and typical of previous auras except that one or more aura symptoms persists for ≥1 week
C. Neuroimaging shows no evidence of infarction
D. Not better accounted for by another ICHD-3 diagnosis.

Comments:
Persistent aura symptoms are rare but well documented. They are often bilateral and may last for months or years. The one-week limit in criterion C is based on the opinion of experts and should be formally studied.

Diagnostic work-up must distinguish 1.4.2 Persistent aura without infarction from 1.4.3 Migrainous infarction, and exclude symptomatic aura due to cerebral infarction of other causes. Attacks lasting more than one hour and less than one week are coded 1.5.2 Probable migraine with aura.