Headache following, and caused by, interruption in chronic use of or exposure to a medication or substance other than those described above.
- Headache fulfilling criterion C
- Daily intake of a substance other than those described above for >3 months, which has been interrupted
- Evidence of causation demonstrated by both of the following:
- headache has developed in close temporal relation to withdrawal from use of the substance
- headache has resolved within 3 months after total withdrawal from use of the substance
- Not better accounted for by another ICHD-3 diagnosis.
It has been suggested, but without sufficient evidence, that withdrawal from chronic use of the following substances may cause headache: corticosteroids, tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs), non-steroidal anti-inflammatory drugs (NSAIDs).
There may be other substances not yet recognized.