8.3.4 Headache attributed to withdrawal from chronic use of other substance

Description:

Headache following, and caused by, interruption in chronic use of or exposure to a medication or substance other than those described above.

Diagnostic criteria:
  1. Headache fulfilling criterion C
  2. Daily intake of a substance other than those described above for >3 months, which has been interrupted
  3. Evidence of causation demonstrated by both of the following:
    1. headache has developed in close temporal relation to withdrawal from use of the substance
    2. headache has resolved within 3 months after total withdrawal from use of the substance
  4. Not better accounted for by another ICHD-3 diagnosis.
Comments:

It has been suggested, but without sufficient evidence, that withdrawal from chronic use of the following substances may cause headache: corticosteroids, tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs), non-steroidal anti-inflammatory drugs (NSAIDs).

There may be other substances not yet recognized.